Ki-67 (SP6) Rabbit Monoclonal Antibody
Specialties: Anatomic Pathology Breast/Gynecological Pathology
The Ki-67 antigen is a nuclear, non-histone protein that is present in proliferating cells.1 Though its specific role is largely postulated and still yet to be determined, Ki-67’s presence during cellular division makes it an excellent target for labeling rapidly growing malignancies.1-4 Given that its presence correlates with cell proliferation, the immunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion’s growth fraction.
- Sun, Xiaoming, and Paul D Kaufman. "Ki-67: more than a proliferation marker." Chromosoma vol. 127,2 (2018): 175-186.
- Pathmanathan, Nirmala, and Rosemary L Balleine. "Ki67 and proliferation in breast cancer." Journal of clinical pathology vol. 66,6 (2013): 512-6.
- Cirqueira, Magno Belém et al. "Effect of Ki-67 on Immunohistochemical Classification of Luminal A to Luminal B Subtypes of Breast Carcinoma." The breast journal vol. 21,5 (2015): 465-72.
- Shivaprasad, Nandish Vastrad et al. "Ki-67 immunostaining in astrocytomas: Association with histopathological grade - A South Indian study." Journal of neurosciences in rural practice vol. 7,4 (2016): 510-514.
Specifications
- Reactivity: paraffin
- Control: Tonsil (Nuclear)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 6.0 (CMC27531060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 25.0 mL predilute ready-to-use | 275R-10 |
| 0.1 mL concentrate | 275R-14 |
| 0.5 mL concentrate | 275R-15 |
| 1.0 mL concentrate | 275R-16 |
| 1.0 mL predilute ready-to-use | 275R-17 |
| 7.0 mL predilute ready-to-use | 275R-18 |
For in vitro diagnostic (IVD) use in Canada
| 25.0 mL predilute ready-to-use | 275R-10 |
| 0.1 mL concentrate | 275R-14 |
| 0.5 mL concentrate | 275R-15 |
| 1.0 mL concentrate | 275R-16 |
| 1.0 mL predilute ready-to-use | 275R-17 |
| 7.0 mL predilute ready-to-use | 275R-18 |
For in vitro diagnostic (IVD) use in Europe
| 25.0 mL predilute ready-to-use | 275R-10 |
| 0.1 mL concentrate | 275R-14 |
| 0.5 mL concentrate | 275R-15 |
| 1.0 mL concentrate | 275R-16 |
| 1.0 mL predilute ready-to-use | 275R-17 |
| 7.0 mL predilute ready-to-use | 275R-18 |
For research use only (RUO) in Japan
| 25.0 mL predilute ready-to-use (RUO) | 275R-10-RUO |
| 0.1 mL concentrate (RUO) | 275R-14-RUO |
| 0.5 mL concentrate (RUO) | 275R-15-RUO |
| 1.0 mL concentrate (RUO) | 275R-16-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 275R-17-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 275R-18-RUO |
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