Myelocytes in bone marrow are labelled by anti-myeloperoxidase.
Myeloperoxidase Rabbit Polyclonal Antibody
Specialties: Hematopathology
Updated: 2022-10-13 15:02:42
Myeloperoxidase (MPO) is a peroxidase that catalyzes the conversion of chloride and hydrogen peroxide to hypochlorite, producing a potent antimicrobial effect. Myeloperoxidase is present in granulocytes and monocytes and cells of myeloid lineage in the bone marrow. Anti-myeloperoxidase immunohistochemistry is useful for identification of benign and malignant myeloid cell populations, including acute myeloid leukemia.1-5
- Pinkus, G S, and J L Pinkus. "Myeloperoxidase: a specific marker for myeloid cells in paraffin sections." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc vol. 4,6 (1991): 733-41.
- Markoc, Fatma et al. "Granulocytic sarcomas: difficulties in diagnosis." Tumori vol. 96,1 (2010): 149-53.
- Alexiev, Borislav A et al. "Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study." Diagnostic pathology vol. 2 42. 31 Oct. 2007.
- Saravanan, L, and S Juneja. "Immunohistochemistry is a more sensitive marker for the detection of myeloperoxidase in acute myeloid leukemia compared with flow cytometry and cytochemistry." International journal of laboratory hematology vol. 32,1 Pt 1 (2010): e132-6.
- Manaloor, E J et al. "Immunohistochemistry can be used to subtype acute myeloid leukemia in routinely processed bone marrow biopsy specimens. Comparison with flow cytometry." American journal of clinical pathology vol. 113,6 (2000): 814-22.
Specifications
- Reactivity: paraffin
- Control: Bone Marrow (Cytoplasmic)
- Dilution Range: 1:100-1:500 *
Package Inserts
IFU
- IVD Rev. 6.0 (CMC28917060)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 289A-74 |
| 0.5 mL concentrate | 289A-75 |
| 1.0 mL concentrate | 289A-76 |
| 1.0 mL predilute ready-to-use | 289A-77 |
| 7.0 mL predilute ready-to-use | 289A-78 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 289A-74 |
| 0.5 mL concentrate | 289A-75 |
| 1.0 mL concentrate | 289A-76 |
| 1.0 mL predilute ready-to-use | 289A-77 |
| 7.0 mL predilute ready-to-use | 289A-78 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 289A-74 |
| 0.5 mL concentrate | 289A-75 |
| 1.0 mL concentrate | 289A-76 |
| 1.0 mL predilute ready-to-use | 289A-77 |
| 7.0 mL predilute ready-to-use | 289A-78 |
For research use only (RUO) in Japan
| 0.1 mL concentrate (RUO) | 289A-74-RUO |
| 0.5 mL concentrate (RUO) | 289A-75-RUO |
| 1.0 mL concentrate (RUO) | 289A-76-RUO |
| 1.0 mL predilute ready-to-use (RUO) | 289A-77-RUO |
| 7.0 mL predilute ready-to-use (RUO) | 289A-78-RUO |
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