FOXA1 (2F83) Mouse Monoclonal Antibody
Specialties: Breast/Gynecological Pathology
Forkhead box A1 (FOXA1), also known as hepatocyte nuclear factor 3 alpha (HNF3a), is a transcription factor associated with embryonic development of multiple endoderm-derived organ systems. Anti-FOXA1 reactivity is seen in certain carcinomas of the breast, normal breast ductal epithelium, and epithelium in various organs. The Anti-FOXA1 immunohistochemical reagent is useful for sub-classification of breast carcinoma.1
- Albergaria A, et al. Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours. Breast Cancer Res. 2009; 11:1-15
- Thorat MA, et al. Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis. J Clin Pathol. 2008; 61:327-32.
- Robinson JL, et al. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. EMBO J. 2011; 30:3019-27.
Specifications
- Reactivity: paraffin
- Visualization: nuclear
- Control: breast carcinoma
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC40521030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 405M-14 |
| 0.5 mL concentrate | 405M-15 |
| 1 mL concentrate | 405M-16 |
| 1 mL predilute | 405M-17 |
| 7 mL predilute | 405M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 405M-14 |
| 0.5 mL concentrate | 405M-15 |
| 1 mL concentrate | 405M-16 |
| 1 mL predilute | 405M-17 |
| 7 mL predilute | 405M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 405M-14 |
| 0.5 mL concentrate | 405M-15 |
| 1 mL concentrate | 405M-16 |
| 1 mL predilute | 405M-17 |
| 7 mL predilute | 405M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 405M-14-RUO |
| 0.5 mL concentrate | 405M-15-RUO |
| 1 mL concentrate | 405M-16-RUO |
| 1 mL predilute | 405M-17-RUO |
| 7 mL predilute | 405M-18-RUO |
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