CD4 (EP204) Rabbit Monoclonal Antibody
Specialties: Hematopathology
CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3
- Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003.
- Akiyama T, et al. Pathol Int. 2008; 58:626-34.
- Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, membranous
- Control: tonsil, lymph node
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 2.0 (CMC10432020)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 104R-24 |
| 0.5 mL concentrate | 104R-25 |
| 1 mL concentrate | 104R-26 |
| 1 mL predilute | 104R-27 |
| 7 mL predilute | 104R-28 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 104R-24 |
| 0.5 mL concentrate | 104R-25 |
| 1 mL concentrate | 104R-26 |
| 1 mL predilute | 104R-27 |
| 7 mL predilute | 104R-28 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 104R-24 |
| 0.5 mL concentrate | 104R-25 |
| 1 mL concentrate | 104R-26 |
| 1 mL predilute | 104R-27 |
| 7 mL predilute | 104R-28 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 104R-24-RUO |
| 0.5 mL concentrate | 104R-25-RUO |
| 1 mL concentrate | 104R-26-RUO |
| 1 mL predilute | 104R-27-RUO |
| 7 mL predilute | 104R-28-RUO |
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