Glucagon (EP74) on pancreatic neuroendocrine tumor.
Glucagon (EP74) Rabbit Monoclonal Antibody
Specialties: Anatomic Pathology
Updated: 2017-05-24 08:46:09
Pancreatic islets (islets of Langerhans) contain several cell types, including glucagon secreting alpha cells and insulin secreting beta cells, that work together to maintain glucose homeostasis.1-2 Glucagon is a peptide hormone that increases blood glucose through gluconeogenesis and glycogenolysis.1-3 Anti-glucagon labels glucagon secreting cells of both normal and neoplastic origin.
- Quesada I, et al. Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes. J Endocrinol. 2008; 199:5-19.
- Gurlo T, et al. Evaluation of immunohistochemical staining for glucagon in human pancreatic tissue. J Histotechnol. 2016; 39:8-16.
- Wewer Albrechtsen NJ, et al. The biology of glucagon and the consequences of hyperglucagonemia. Biomark Med. 2016; 10:1141-51.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: pancreas
- Dilution Range: 1:100-1:200*
Package Inserts
IFU
- IVD Rev. 3.0 (CMC25931030)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 259R-14 |
| 0.5 mL concentrate | 259R-15 |
| 1 mL concentrate | 259R-16 |
| 1 mL predilute | 259R-17 |
| 7 mL predilute | 259R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 259R-14 |
| 0.5 mL concentrate | 259R-15 |
| 1 mL concentrate | 259R-16 |
| 1 mL predilute | 259R-17 |
| 7 mL predilute | 259R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 259R-14 |
| 0.5 mL concentrate | 259R-15 |
| 1 mL concentrate | 259R-16 |
| 1 mL predilute | 259R-17 |
| 7 mL predilute | 259R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 259R-14-RUO |
| 0.5 mL concentrate | 259R-15-RUO |
| 1 mL concentrate | 259R-16-RUO |
| 1 mL predilute | 259R-17-RUO |
| 7 mL predilute | 259R-18-RUO |
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