Cytokeratin 14 (LL002) Mouse Monoclonal Antibody
Specialties: Anatomic Pathology
Cytokeratin 14 is a member of the Type I family of cytokeratins and is generally expressed in the basal cell layer of squamous epithelium. The cytokeratin 14 protein forms a heterotetramer with homodimers of cytokeratin 5 to contribute to the structural integrity of the intracellular cytoskeletal network.1 Anti-cytokeratin 14 has immunohistochemical utility as an aid in distinguishing squamous cell carcinomas from other tumors of epithelial origin.2
- Moll R, et al. The human keratins: biology and pathology. Histochem Cell Biol. 2008; 129:705-33.
- Chu PG, et al. Cytokeratin 14 expression in epithelial neoplasms: a survey of 435 cases with emphasis on its value in differentiating squamous cell carcinomas from other epithelial tumours. Histopathology. 2001; 39:9-16.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic
- Control: squamous cell carcinoma
- Dilution Range: 1:100-1:500*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC31421040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 314M-14 |
| 0.5 mL concentrate | 314M-15 |
| 1 mL concentrate | 314M-16 |
| 1 mL predilute | 314M-17 |
| 7 mL predilute | 314M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 314M-14 |
| 0.5 mL concentrate | 314M-15 |
| 1 mL concentrate | 314M-16 |
| 1 mL predilute | 314M-17 |
| 7 mL predilute | 314M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 314M-14 |
| 0.5 mL concentrate | 314M-15 |
| 1 mL concentrate | 314M-16 |
| 1 mL predilute | 314M-17 |
| 7 mL predilute | 314M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 314M-14-RUO |
| 0.5 mL concentrate | 314M-15-RUO |
| 1 mL concentrate | 314M-16-RUO |
| 1 mL predilute | 314M-17-RUO |
| 7 mL predilute | 314M-18-RUO |
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