ALK Protein (ALK-1) Mouse Monoclonal Antibody
Specialties: Hematopathology
Anaplastic lymphoma kinase (ALK) is a novel receptor protein-tyrosine kinase.1 ALK can create a fusion protein with a nuclear protein gene called nucleophosmin (NPM) via the amino terminus of NPM and the catalytic domain of ALK.2 The product of this fusion protein is oncogenic.1 Studies have found this chromosomal translocation in most anaplastic large-cell non-Hodgkin's lymphomas, making ALK a good marker for anaplastic large cell lymphomas.2
- Iwahara T, et al. Oncogene. 1997; 14:439-49.
- Morris SW. Science. 1994; 263:1281-4.
Specifications
- Reactivity: paraffin
- Control: Anaplastic large cell lymphoma (Cytoplasmic, Nuclear)
- Dilution Range: 1:25-1:100 *
Package Inserts
IFU
- IVD Rev. 4.0 (CMC20421040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 204M-14 |
| 0.5 mL concentrate | 204M-15 |
| 1 mL concentrate | 204M-16 |
| 1 mL predilute | 204M-17 |
| 7 mL predilute | 204M-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 204M-14 |
| 0.5 mL concentrate | 204M-15 |
| 1 mL concentrate | 204M-16 |
| 1 mL predilute | 204M-17 |
| 7 mL predilute | 204M-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 204M-14 |
| 0.5 mL concentrate | 204M-15 |
| 1 mL concentrate | 204M-16 |
| 1 mL predilute | 204M-17 |
| 7 mL predilute | 204M-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 204M-14-RUO |
| 0.5 mL concentrate | 204M-15-RUO |
| 1 mL concentrate | 204M-16-RUO |
| 1 mL predilute | 204M-17-RUO |
| 7 mL predilute | 204M-18-RUO |
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