Rabbit monoclonal anti-calretinin stains mesothelioma cells in predominantly cytoplasmic pattern.
Calretinin (SP13) Rabbit Monoclonal Antibody
Specialties: Cytopathology Pulmonary Pathology
Updated: 2017-05-24 08:46:09
Calretinin is a 29-kDa calcium-binding protein thought to play a role in the cell cycle.1 Anti-calretinin labels mesothelial and Leydig cells under normal and neoplastic conditions.2,3 Anti-calretinin has been shown to be useful in differentiating mesothelioma from adenocarcinomas of the lung and other sources.4-6
- Rogers JH. Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons. J Cell Biol. 1987; 105:1343-53.
- Doglioni C, et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol. 1996; 20:1037-46.
- Augusto D, et al. Calretinin: a valuable marker of normal and neoplastic Leydig cells of the testis. Appl Immunohistochem Mol Morphol. 2002; 10:159-62.
- Barberis MC, et al. Calretinin. A selective marker of normal and neoplastic mesothelial cells in serous effusions. Acta Cytol. 1997; 41:1757-61.
- Ordóñez NG. The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma. Am J Surg Pathol. 2003; 27:1031-51.
- Abutaily AS, et al. Immunohistochemistry in the distinction between malignant mesothelioma and pulmonary adenocarcinoma: a critical evaluation of new antibodies. J Clin Pathol. 2002; 55:662-8.
Specifications
- Reactivity: paraffin
- Visualization: cytoplasmic, nuclear
- Control: mesothelioma
- Dilution Range: 1:25-1:100*
Package Inserts
IFU
- IVD Rev. 4.0 (CMC23231040)
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Ordering Information
For in vitro diagnostic (IVD) use in USA
| 0.1 mL concentrate | 232R-14 |
| 0.5 mL concentrate | 232R-15 |
| 1 mL concentrate | 232R-16 |
| 1 mL predilute | 232R-17 |
| 7 mL predilute | 232R-18 |
For in vitro diagnostic (IVD) use in Canada
| 0.1 mL concentrate | 232R-14 |
| 0.5 mL concentrate | 232R-15 |
| 1 mL concentrate | 232R-16 |
| 1 mL predilute | 232R-17 |
| 7 mL predilute | 232R-18 |
For in vitro diagnostic (IVD) use in Europe
| 0.1 mL concentrate | 232R-14 |
| 0.5 mL concentrate | 232R-15 |
| 1 mL concentrate | 232R-16 |
| 1 mL predilute | 232R-17 |
| 7 mL predilute | 232R-18 |
For research use only (RUO) in Japan
| 0.1 mL concentrate | 232R-14-RUO |
| 0.5 mL concentrate | 232R-15-RUO |
| 1 mL concentrate | 232R-16-RUO |
| 1 mL predilute | 232R-17-RUO |
| 7 mL predilute | 232R-18-RUO |
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